ROLE OF TUBERCULASIS AMH IN INFERTILITY. Tuberculosis (TB) can indeed affect fertility, and the role of tuberculous endometritis in infertility, sometimes referred to as "Tuberculous Endometritis-associated Infertility, " is significant. Here are some key points to consider: Pathophysiology: Tuberculosis primarily affects the lungs but can spread through the bloodstream to other organs, including the reproductive organs. Genital tuberculosis occurs when TB bacteria affect the uterus, fallopian tubes, ovaries, or other parts of the reproductive system. Impact on the Uterus: Tuberculous endometritis can lead to the formation of granulomas in the endometrial lining of the uterus. These granulomas can cause scarring and adhesions (Asherman's syndrome), which may lead to infertility. Scarring can interfere with the implantation of a fertilized egg or cause irregularities in menstruation. Fallopian Tubes: Tuberculosis can also affect the fallopian tubes, leading to tubal obstruction. This obstruction can prevent the egg from traveling from the ovary to the uterus or block the sperm from reaching the egg, thereby causing infertility. Diagnosis: Diagnosing tuberculous endometritis can be challenging because symptoms may not be specific and can mimic other conditions. Imaging studies, endometrial biopsy, and cultures for Mycobacterium tuberculosis are typically used for diagnosis. Treatment: Treatment involves a combination of anti-tubercular medications for a prolonged period (usually 6-9 months). Surgical intervention may be necessary in cases of severe tubal damage or extensive uterine involvement. Prognosis: Early detection and treatment are crucial for a better prognosis. However, the extent of damage to the reproductive organs prior to treatment can significantly impact fertility outcomes. In summary, tuberculous endometritis can lead to infertility due to scarring and adhesions in the uterus and fallopian tubes. Early diagnosis and appropriate treatment are essential to preserve fertility and improve reproductive outcomes in affected individuals.